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An idea for the sole survivor,

Ok so, the bombs drop and the quality of life massively decreases (of course) along with the quality of air. At first it completely toxic and many of these who survive the initial bombs drop dead form the air pollution. But we as humans are incredibly resilient and learn to adapt, as time goes on people grow increasingly more resistant to the toxic air. 200 hundred years later, basically everyone in the commonwealth and all over post apocalyptic America is immune to the toxic air. But the sole survivor ,being pre war and trap in a freezer with no exposure to the radiation world (except for like 5 minutes when Kellogg kidnapped Shaun, waking everyone up). Hasn’t grown the immunity to the toxic air like everyone else. So they have to wear a gas mask or a rebreather everywhere or they choke to death cause of the radiation.

Does this make sense?